Cure disease – Heiki Thu, 21 Oct 2021 22:07:54 +0000 en-US hourly 1 Cure disease – Heiki 32 32 New treatment for the painful side effects of blood cancer Thu, 21 Oct 2021 21:11:39 +0000

The use of BK virus (BKV) specific T cells from healthy donors to treat BKV-associated hemorrhagic cystitis, a painful side effect associated with immunosuppression of stem cell transplants, may relieve the complication more quickly in patients. with lymphoma or leukemia, depending on the results of the trial.

“What was very important was that within a week after the administration of the cells, the majority of the patients’ symptoms improved,” said Dr Katy Rezvani, professor of stem cell transplantation and therapy. cell phone at the University of Texas MD Anderson Cancer Center in Houston and lead author of the study, said in an interview with CURE®. “The effect of the cells is relatively quick.”

BKV-associated hemorrhagic cystitis occurs more frequently in patients with leukemia or lymphoma who have received allogeneic stem cell transplant therapy. As a result, this can lead to patients having blood in their urine and passing clots, which can cause urinary retention (difficulty urinating or completely emptying the bladder) and, in more severe cases, kidney disease. .

In patients who receive stem cell transplants, those who have a half-match (when patients have only a few genetic similarities to the donor’s immune system) are at an increased risk of BKV-associated hemorrhagic cystitis because they are more immunocompromised. About 40% of patients who have a half-game develop this complication.

In the phase 2 trial, BKV-specific T cells, which recognize and attack BKV, from healthy donors were administered once intravenously, with the option of receiving additional doses every two weeks if necessary. Of the 59 patients included in the trial, 67.7% had complete (all symptoms resolved) or partial (almost all symptoms resolved) responses within 14 days. This rate rose to 81.6% after 28 days.

Some intolerance has been observed in patients who have been previously treated with steroids, which can kill T cells. There have been no side effects, and there have been no reports of new liver disease or disease. graft versus host (GVHD, which occurs when donor cells attack patient cells) associated with antiviral T cells, with the exception of a few cases of cutaneous GVHD. this resolved quickly with corticosteroids.

This treatment has the potential to stop the vicious cycle that accompanies the current standard of care, which consists of hospitalization with continuous irrigation of the bladder (using a catheter to wash the bladder) and an infusion of morphine for help patients tolerate pain, according to Rezvani. .

“This outpatient treatment saves patients from having to be admitted (to the hospital), which is wonderful because patients come to the hospital with one thing, they stay in the hospital for a few weeks, and then they develop. other complications, ”Rezvani explained. “They start to get other infections, they get pneumonia, they are malnourished, etc.”

According to Rezvani, a donor can produce up to 50 doses of T cells, which are frozen until needed. “Every time the patient comes (to the hospital), within 24 hours, we can treat them,” she said.

It is worth noting that the therapy is only available to MD Anderson, so patients with the complication should come to the health center to receive it – an option that may not be possible due to their physical condition. or their finances. “Hopefully we will get to a situation where we can start a multicentre study at some point,” said Rezvani, which would make care more accessible to patients. “In the meantime, I think the biggest limitation is really that patients will have to come to MD Anderson to receive the treatment, and for many patients with the terrible BKV hemorrhagic cystitis, that is obviously not possible.”

Until then, Rezvani is focusing on the next generation of treatment: genetically modifying BKV-specific T cells that are more resistant to steroids, thus broadening the spectrum of patients that treatment might help.

“It is important to realize that the use of immunotherapy against viruses and cancers (has) opened a very exciting new era of treatment for our patients,” she concluded. “We’re learning a lot more about the immune system (and harnessing) the power of the immune system to fight infections and cancer. … I think the field will continue to grow, and many other such treatments to target both viruses and cancers (will) be available. “

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Michael J. Fox’s Parkinson’s Charity Raised Over $ 1 Billion Tue, 19 Oct 2021 08:52:00 +0000 Michael J. Fox’s Parkinson’s Disease Research and Patient Advocacy Fund has raised more than US $ 1 billion over the past two decades, according to a report by Variety Journal of Hollywood.

Two years after going public with his diagnosis in 1998, the actor launched the Michael J. Fox Foundation for Parkinson’s Research to help fund research into therapies and cures – and he will belatedly mark the twenty years with the 2020 installment of his fundraising gala, A Funny Thing Happened on the Way to Cure Parkinson’s, which takes place this week after being delayed by the Covid crisis.

“All I wanted to do was book that McDonalds commercial,” the actor told The Roadmap as he reflected on the early days of his career and about the milestones. “I had no idea I would try to find a cure for Parkinson’s disease.”

A cure for Parkinson’s disease is a great ambition for the actor and his team, but the foundation claims to have participated directly in the development of several therapies. “These are therapies that have made a lot of life better for a lot of people.

“I enjoy life more. I’m more comfortable in my skin than 20 years ago. I can sit back and be calm. I couldn’t do that 25 years ago. These are the drugs, drug cocktails and therapies that we’ve been a part of. “

He also spoke about patient advocacy, particularly in terms of communication between patients and the medical and academic communities – thanking CEO and co-founder Deborah W. Brooks. “She’s just magic.”

The next step in identifying the risk and treating the disease lies in the biomarkers, the actor explains. “If we can find ways to identify the disease before it’s obvious, if we could take a piece of hair and find it, then we could treat it prophylactically and then maybe you don’t. not get. “

“What I’m most proud of is how we’ve galvanized this community. We can get things done,” he concluded, looking for a cure.

“I am committed to it. I will not stop until this happens.”

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Facebook Users Falsely Claim “Marijuana Preserved With Honey Cures 40 Health Problems” Mon, 18 Oct 2021 04:26:07 +0000 Copyright AFP 2017-2021. All rights reserved.

Facebook posts, shared hundreds of times, claim that “honey preserved marijuana” cures 40 different medical conditions, including Alzheimer’s disease, diabetes and high blood pressure. The messages are misleading; there is no evidence that the purported remedy can cure these conditions. Health experts have said people should see a doctor if they have any health issues.

“Recipe for marijuana preserved with honey, cures 40 different diseases”, we read in Thai Facebook post of September 18 shared over 600 times.

The post lists a variety of health issues, including Alzheimer’s disease, diabetes, and high blood pressure.

“Use the entire cannabis trunk, as well as the leaves, roots and flowers. Cut them into pieces, dry them and leave them for 15 days. Take a teaspoon every day before going to bed “.

Screenshot of the misleading claim shared on Facebook, taken on October 18, 2021

Marijuana has been used as a traditional herb for centuries in Thailand, but has been banned decades ago.

In February 2019, Thailand legalized the use of marijuana for medical purposes.

In December 2020, marijuana was eliminated from a government list of “harmful drugs,” meaning it is now legal to plant it in the country if government approval is obtained.

A similar claim was shared here, here and here on Facebook.

The claim is misleading: Experts say there is not enough evidence to prove that the alleged remedy cures any health problem.

‘No proof’

Dr Khwanchai Wisitanon, Deputy Director of Thailand Department of Traditional and Alternative Thai Medicine said there was no evidence to prove the effectiveness of the alleged remedy.

“Based on the medical record, there is no research to support this claim,” he told AFP.

“If you are diagnosed with a certain disease, you should seek medical advice from health professionals for medical treatment.”

Dr Thiravat Hemachudha, a medical marijuana expert at Chulalongkorn University, also said there was not enough evidence to prove that the alleged recipe can “cure” diseases.

“There is no evidence to suggest that the claim is correct,” he told AFP.

“It’s true that marijuana has anti-inflammatory properties, but patients shouldn’t be relying on it to get better. They should always see a professional doctor.”

Although marijuana may have properties that can relieve some symptoms, it cannot “cure” diseases, according to Pakakrong Kwankhao, chief of staff. Chaopraya Abhaiphubejhr Hospital Thai Evidence-Based Traditional Medicine and Herbal Medicine Center.

“Marijuana can help alleviate some symptoms. It can ease the patient’s pain or make the patient rested or happy. However, there is still a lack of evidence that it can be used to” cure “any disease,” he said. she told AFP.

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Annual Napa at Newport Wine Event November 6 CureDuchenne Benefits Sat, 16 Oct 2021 22:01:37 +0000
Napa at Newport 2020

The annual Newport Napa Wine Auction, based in Newport Beach, CureDuchenne, barely beat Covid closures last year when the fundraiser brought in $ 1 million at the 2020 event which was held on February 29.

The pandemic has postponed this year’s Napa to Newport, but it returns next month, bigger and better than ever.

CureDuchenne and Vintner President Bryant Estate are hosting the seventh annual Napa Wine Auction in Newport and Dinner on Saturday, November 6 at the Waldorf Astoria Monarch Beach Resort in Dana Point.

This acclaimed event brings together renowned Napa Valley winemakers, wine collectors and prominent philanthropists from the Orange County area to raise funds for CureDuchenne, a global non-profit organization aimed at saving the lives of 300 000 children and young adults living with Duchenne muscular dystrophy.

Duchenne muscular dystrophy is a fatal genetic disease. It is the most common and serious form of muscular dystrophy. Patients are usually diagnosed as toddlers, lose the ability to walk in their early teens, and often succumb to the disease in their mid-twenties.

Napa at Newport 2020

For this year’s Napa n Newport, over 45 of Napa’s top wineries will collectively offer a grand tasting of coveted rare wines. Guests are treated to dining tables hosted by winemakers, an exquisite dinner menu designed by Chef Chris Shepherd, named one of America’s Top 10 New Chefs by Food & Wine in 2013 and a recipient of the James Award Best Chef Beard 2014: Southwest.

A lively auction will feature vintage wines, exotic getaways and unique experiences.

Renowned sommelier Michael Jordan is the curator of Napa wines in Newport. He knows wine incredibly well, and for good reason: Jordan holds a Master Sommelier degree from the Court of Master Sommeliers as well as a Certified Wine Educator degree from the Society of Wine Educators. He is one of 15 people in the world to hold both degrees.

He has helped put together an impressive list of winemakers, including Alpha Omega, Darioush, Hundred Acre, Opus One, OVID and many more.

A participating winemaker has local ties: Riverain co-founder Steve Nordhoff is the founding lawyer of Nordhoff Bengfort, a Newport Beach-based law firm, while his partner Dean Gray and his wife Laurie live in Newport Beach (Laurie takes many photos for the Riverain Etiquettes).

Napa at Newport 2020

To date, Napa guests and donors in Newport have helped raise over $ 6 million for CureDuchenne. Founded in Newport Beach by the parents of a son living with Duchenne, CureDuchenne uses an innovative model of venture capital philanthropy to fund groundbreaking research for treatment and support programs for people living with the disease, while advocating for early diagnosis and better access to treatment.

Individual tickets are still available. For more information on tickets, sponsorships and participating wineries, visit

About CureDuchenne: CureDuchenne is recognized as a global leader in research, patient care and innovation to improve and extend the lives of people with Duchenne muscular dystrophy. As the main genetic killer of young boys, Duchenne affects more than 300,000 people living today.

CureDuchenne is dedicated to finding and funding a cure for Duchenne by breaking the traditional charitable mold through an innovative model of venture philanthropy that funds groundbreaking research, early diagnosis and community education.

For more information on how to help raise awareness and fund research, please visit

Napa at Newport 2020

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Still standing through the breast cancer storm Fri, 15 Oct 2021 17:42:35 +0000

In honor of Breast Cancer Awareness Month, businesses, sports organizations, schools and places of worship honor survivors and call for treatment.

However, for countless women around the world and I, it’s over 31 days of wearing pink ribbons, 3K events, and fundraising.

Let’s not forget the men who survived breast cancer.

October has the same appeal as any other time on the calendar when you are a survivor of this disease.

Designating this month just gives a greater platform to share a testimony of prayer, faith and deliverance.

“But he was pierced for our transgressions, he was crushed for our iniquities; the chastisement that brought us peace was upon him, and by his wounds we were healed.” – Isaiah 53: 5 NIV