Cure disease – Heiki Wed, 11 May 2022 05:13:41 +0000 en-US hourly 1 Cure disease – Heiki 32 32 ‘Fit and healthy’ mum dies of rare illness after co-workers spot her coughing at work Wed, 11 May 2022 05:13:41 +0000

A Wigan mum has died of a rare illness after colleagues noticed her coughing at work. Anne Doran was fit and healthy, always hitting the gym and taking long walks before she was diagnosed with idiopathic pulmonary fibrosis (IPF).

The disease, which affects only 50 in 100,000 people and has no cure, has left her struggling to breathe and bedridden. ‘Inspirational’ Anne was diagnosed with IPF in 2014 aged 58 after colleagues at Royal Liverpool University Hospital noticed she was coughing.

The former senior executive at Royal Liverpool Hospital, who worked as a magistrate and school governor despite battling the disease, died in August 2020. His family are campaigning to raise money for charity Action for Pulmonary Fibrosis .

Anne’s daughter, Louise Doran, told the Manchester Evening News: ‘She was going for a walk, going to the gym, you know she was healthy. “Then it happened and at first she wasn’t on oxygen and she could still move around.

“She was going to work coughing, and someone picked her up and said, ‘You better get it checked out’, so she did and had a lung biopsy and she was diagnosed as a idiopathic pulmonary fibrosis.

Anne Doran started working as a nurse at the Royal Liverpool Hospital around 1970

“Then she had to take oxygen and she could do less and less. In the end, she was sitting on the couch, and just by raising her arm or moving a space, the oxygen in his blood was diminishing.

“Even though she was getting oxygen, her lungs couldn’t handle it because there were scars. It’s so limiting, you can’t talk, you eat less and less.

Ann Doran was diagnosed with idiopathic pulmonary fibrosis eight years ago
Ann Doran was diagnosed with idiopathic pulmonary fibrosis eight years ago

“You end up being bedridden and unfortunately in my mum’s experience, once you get to that point you probably don’t have much left.”

Currently, only two drugs slow the progression of the disease. Limited clinical trials exist, as do lung transplants, but they are not available for all patients.

Louise added: “They don’t know what caused it. They asked him all the usual questions: did you work in a mine, did you raise pigeons, do you smoke? And the answer was no to all those questions, so they couldn’t identify what it was.

“There are quite a few people who have it and they don’t know what caused it. There are different groups on Facebook with advice and tips for people with IPF, so they can try to support each other.

Ann and Tom Doran have been married for 45 years
Ann and Tom Doran have been married for 45 years

“But there are still people struggling there now, just like my mum was two years ago and there doesn’t seem to have been a lot of change. Charities are doing research to try to find a cure, which is great, but day-to-day things really could be so much better.

“It’s such a poor quality of life, it’s awful to see.”

Now Louise and her sister Jenny have organized a charity event in Stockport to raise money for Action for Pulmonary Fibrosis which has helped their mother. They arranged an audience with author and historian Alison Weir.

The event will take place at the Guildhall in Stockport on June 30. They have also organized a re-enactment group to appear in costume and are holding a raffle. Prizes include a Dyson vacuum cleaner worth £379.99 plus autographed books donated by Tracy Borman and Tracy Chevalier.

Alison will be available for book signings and will be in conversation with Dr Martin Heale, Reader in Medieval History at the University of Liverpool.

Tickets cost £10, to book a ticket for the event, Click here .

]]> People who have never had Covid may hold the genetic key to a cure Mon, 09 May 2022 12:20:54 +0000

Around one in 10 people in England are still believed to be Covid-free – and scientists now believe this minority could pave the way for a cure for the deadly virus.

Even though the highly transmissible variant of Omicron that swept the world towards the end of 2021 continues to be the dominant strain, there are people who have not tested positive throughout the pandemic.

Scientists now looking to study this small demographic group to see if their genes could help future treatment – ​​or even prevent Covid infection altogether.

András Spaan, a clinical microbiologist at Rockefeller University in New York, is leading the hunt for what could be causing this resistance to Covid, with particular emphasis on their genetic material.

He said the Washington Post: “What we are looking for are potentially very rare genetic variants with a very large impact on the individual.”

He leads the international study, which already has 700 participants. Scientists are also looking at more than 5,000 additional people who think they might be immune to the virus.

Health workers, who went without face masks at the height of the pandemic and still managed to test negative for Covid on a weekly basis, are among those being screened for signs of immunity.

So how many people still haven’t caught the Covid?

Journalist John Burn-Murdoch published a graph for the Financial Times last week explaining that – based on data from the Office of National Statistics (ONS) – nine out of 10 people in England have tested positive for Covid at a given time of the pandemic.

PA GraphicsPress Association Images

People who tested positive for Covid-19 in private households in the UK

Positive cases are currently declining, but the number of infections has fluctuated throughout the pandemic, depending on the variant that is spreading and the status of vaccination of the general population.

Yet, even though some people have said they have caught Covid on several occasions, there is still a category that thinks they have not caught the virus at all.

The United States Centers for Disease Control and Prevention estimates that six in 10 people across the United States have had Covid at some point, at least once.

According to data website, there had been almost 514 million cases of Covid as of May 1, 2022 – which certainly makes people who avoided it an anomaly.

What could make some people immune to Covid?

Experts believe some people may have fewer receptors in their nose, throat and lungs, meaning the virus has a harder time binding to their bodies.

Alternatively, this minority could have been previously exposed to a similar virus that gave their immune systems a head start against Covid.

They may also be born with a particular immune system already equipped to fight off the virus, making it a genetic problem.

If scientists are able to find out why this small class of people have not been infected, both public health advice and Covid drugs could be vastly improved. It could even help protect the general population from future strains of the virus, which are expected.

However, individual use of masks, vaccines and social distancing could affect the study’s ability to find those who are immune.

Frequent testers, those who wear masks indoors and avoid gatherings or high-risk travel have obviously lowered their risk of catching the virus by their decisions. This means that it had not so much to do with their genetics or their immune system, but their approach to the pandemic.

Bob Wachter, professor and chair of the Department of Medicine at the University of California, San Francisco, also told The Washington Post, “It has to be a combination of caution, circumstance, and luck.”