As the Covid-19 pandemic rages on, here are the 7 Major Medical Wonders of 2021

As the Covid-19 pandemic raged in 2021, the year saw breakthroughs and medical innovations in addition to the release of two new vaccines. From the very first drug approved to treat rare progeria, to the new formulation of insulin that could make therapy affordable for a malaria vaccine, which took years to prepare, here are the seven biggest developments in the field. medicine.

Revolutionary vaccines against Covid-19

Moderna-NIAID’s Spikevax and Pfizer-BioNTech’s Comirnaty have been cleared for emergency use to treat Covid-19 in 2021. As countries rush to save humanity from Covid-19 rabies, experts from Health and physicians have started their journey to understand the characterization of the SARS-COV-2 virus, how it affects the immune system and developed an injection to prevent it. Jabs are the world’s first so-called mRNA vaccines. If a vaccinated person comes into contact with the SARS-CoV-2 virus, the antibodies reproduce and destroy the virus before it replicates uncontrollably. Vaccines prevented hospitalization 100% of the time. The two-dose regimen is 94% effective in treating symptomatic people.

A new treatment for rare progeria

The FDA has approved Zokinvy for the treatment of Hutchinson-Gilford progeria syndrome, a rare condition that causes premature aging. People diagnosed with this disease do not live beyond 15 years. The disease is caused by a genetic mutation that changes proteins in the nuclei of the carrier’s cell. The defective protein (progerin) causes premature cell death. Zokinvy prevents the accumulation of the defective protein. The new drug extends life and also reduces heart and bone problems.

A big step forward in gene therapy

Researchers successfully injected the CRISPR gene editing tool directly into a person’s body to treat genetic liver disease. In a clinical trial involving six people in August 2021, doctors tried to correct a genetic defect that causes a rare liver disease called transthyretin amyloidosis. The gene editing tool aims to correct defective cells in the liver. The treatment, which is still in its first phase of clinical trial, could pave the way for a cure for various genetic diseases.

Game-changing Ebola gunshot

Researchers at biotech company Regeneron have created monoclonal antibodies – molecules made in the lab that mimic the work of the immune system’s natural defenses to target disease. Inmazeb, which is a combination of three antibodies, targets a protein on the surface of the Ebola virus. In a clinical trial, 66.2% of 154 people survived after receiving Inmazeb, compared to 49% of 153 people who did not. While not a sure-fire cure, FDA-approved Inmazeb is cleared for emergency use in the treatment of many viral illnesses.

First malaria vaccine

Malaria kills around half a million people worldwide each year, by some estimates. Mosquirix by GlaxoSmithKline is effective against Plasmoduim falciparum, which is one of the five deadliest parasites that cause malaria and the most common strain in Africa. Although inoculation is 50% effective against severe malaria, it is still one of the best ways to prevent the disease.

Most affordable insulin ever

Semglee by Viatris is a biosimilar insulin recognized by the FDA. It comes in 10ml vials and 3ml pre-filled pens subcutaneously once daily, and is medically identical to Lantus, the brand of insulin.

The very first smart implant

The very first successful knee implantation took place in October. The device can remotely monitor the patient and send information such as steps taken, walking speed, range of motion to the orthopedic surgeon to track recovery. The implant called Persona IQ uses basic material and technology found in pacemakers and provides a lot of information about the patient’s body.

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