AGING AND FERTILITY HEALTH IN WOMEN (PART 2)

Last week, we started a topic on aging and its effects on women’s fertility and well-being. This week we will conclude with some of the ways to preserve female fertility.

HEALTH PRESERVATION OF FEMALE FERTILITY

LIFESTYLE CHANGE

Our habits and lifestyles are lifestyle factors and can impact our overall health, well-being and fertility. Developing healthy habits has a significant impact on your overall health and fertility. You may not be able to control medical conditions that affect your ability to conceive, but you can control several lifestyle habits known to impair fertility, such as smoking, alcohol, and caffeine. Maintain a healthy weight, as being significantly overweight or underweight can prevent ovulation from occurring normally. Prevent sexually transmitted diseases by using a condom. Infections like chlamydia and gonorrhea are one of the most common causes of infertility in women. Working nights on a regular basis can increase your risk of infertility by altering/disrupting hormone production as a side effect of stress. If you work nights, make an effort to get enough rest while you’re not working.

CRYOPRESERVATION OF GAMETES/EMBRYOS

Fertility preservation treatments, such as preserving embryos after IVF or egg retrieval and freezing for later use, are options for women who want to postpone childbearing until their late 30s. or early 40s. Embryo freezing (cryoconservation) has a high success rate, but it requires a male partner or the use of donor sperm. Egg freezing for fertility preservation is a new and proven method. Women who want to use elective egg freezing still have to deal with their age. The results of assisted reproductive technology cycles using frozen eggs become less favorable as the age of women undergoing egg freezing increases.

PRE-IMPLANTATION GENETIC SCREENING

New technologies are now available that will allow embryos to be tested for chromosomal abnormalities. This technology is used to generate embryos during an IVF cycle. This can be especially beneficial for older women. Preimplantation Genetic Testing (PGT) involves removing a small number of cells from each embryo and analyzing them for genetics. Chromosomally normal embryos would be selected for transfer to the womb/womb of the mother. The goal is for PGT/PGS to prevent the transfer of a genetically abnormal embryo with an increase in the number of successful pregnancies and the birth of healthy babies.

EGG DONATION

Treatment options are limited when you’re older, especially if you’re over 42, haven’t had success with previous treatments, or have premature ovarian failure (OPF), commonly known as premature menopause. Egg donation, which involves using eggs donated by a woman in her 20s or early 30s, is a very successful procedure. The high success rate of egg donation shows that the biggest barrier to pregnancy in older women is egg quality, which is age-related. Although the chances of a successful pregnancy in IVF cycles using donor eggs are much higher if you are over 40, many couples or single women in their early 40s will choose to accept the lower probability of get pregnant using their own eggs. At age 43, the chances of getting pregnant through IVF are less than 5% and at age 45, donated eggs are the only feasible option.

The woman who receives the donated eggs is called the “recipient” in an egg donation cycle. Fertility drugs are given to the egg donor to induce the development of many eggs in her ovaries. At the same time, hormone therapy is given to the egg recipient to prepare her uterus to receive the fertilized eggs (embryos). Once the donor eggs are collected, they are fertilized in the laboratory with the sperm of the recipient’s partner. The embryos are transferred to the recipient’s uterus a few days after fertilization. Any embryos that are not transferred can be frozen (cryopreserved) and used in the next cycle.

Egg donor IVF allows a woman to experience pregnancy, childbirth and motherhood. The child, on the other hand, will be genetically related to the father and the egg donor rather than her. Many programs recommend counseling so that all parties involved in an egg donor agreement are aware of the ethical, legal, psychological, and social issues involved. Women in their twenties with proven fertility are ideal donors, as success is highly dependent on the quality of donated eggs.

CONCLUSION

As women age, their fertility naturally declines. However, when the decline begins and how quickly it progresses vary widely among women, but always begin well before menopause. Fertility typically begins to decline in your late 20s or early 30s, and declines more rapidly after age 35. Women who decide to delay pregnancy until age 35 should seek information about appropriate tests and treatments while remaining realistic about their chances. success with infertility treatment. A woman and her partner will be better prepared to make the best decisions if they know all of their options and are aware of their own needs and goals.

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